Optical engineering 1

Optically engineered dynamic materials have a wide range of applications in areas ranging from biomedical imaging to adaptive camouflaging. Within this context, the cephalopod’s camouflaging and color-changing abilities are attributed to reflectin protein-based subcellular reconfigurable structures in their tunable skin architectures. However, engineering and mimicking such dynamics and reversible control over transparencies in living human cells and tissues have remained challenging. In this section of the subgroup, we have designed and engineered human cells that contain reconfigurable reflectin-based photonic architectures and in turn, possess tunable transparency-changing and light-scattering capabilities. We aim to further understand the self-assembly of these proteinaceous photonic structures in vitro and in vivo to predict bulk optical properties, design genetic probes for non-invasive intracellular imaging and generate light-manipulating living materials for optical engineering, biophotonics, and biomedical applications.

Related Publication

Cephalopod-inspired Optical Engineering of Human Cells

Chatterjee, A.; Cerna Sanchez, J. A.; Yamauchi, T.; Taupin, V.; Couvrette, J.; Gorodetsky, A. A.; Nature Communications, 2020, 11, p. 2708.

Article

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