Welcome to the Gorodetsky Group at the University of California, Irvine!

Our group looks to coleoid cephalopods (squids, octopuses, cuttlefish) as muses for the development of bioinspired technologies. In one research thrust, we are leveraging the unique cephalopod skin cell protein reflectin for programming the optical properties of mammalian cells and for electrically controlling the fate of mammalian cells, with our efforts holding relevance for regenerative medicine and engineered living materials. In another research thrust, we are drawing inspiration from cephalopod skin cells for the design and manufacturing of adaptive infrared and thermoregulatory materials, with a focus on applications in next-generation thermal camouflage and sustainable food packaging. Please browse the videos and publications to learn more about the current projects.

Octopus-Inspired Deception and Signaling Systems from an Exceptionally-Stable Acene Variant
Pratakshya, P.; Xu, C.; Dibble, D. J.; Mukazhanova, A.; Liu, P.; Burke, A. M.; Kurakake, R.; Lopez, R.; Dennison, P. R.; Sharifzadeh, S.; Gorodetsky, A. A. Nature Communications, 2023, 14, p. 8528. [Article]
Structure–Function Relationships for Squid Skin-Inspired Wearable Thermoregulatory Materials
Liu, P.; Leung, E. M.; Badshah, M. A.; Moore, C. S.; Gorodetsky, A. A. APL Bioengineering, 2023, 7, p. 046111. [Article]
Squid Leucophore-Inspired Engineering of Optically Dynamic Human Cells
Bogdanov, G.; Chatterjee, A.; Makeeva, N.; Farrukh, A.; Gorodetsky, A. A.; iScience, 2023, 26(7), p. 106854. [Article]